Main Operating Companies


Otsuka Pharmaceutical Co., Ltd.

At Otsuka Pharmaceutical, we are committed to a holistic approach to health and well-being of people and are striving to create innovative, thoroughly-original pharmaceutical and nutraceutical products based on our corporate philosophy Otsuka-people creating new products for better health worldwide.

Corporate Profile

Company Name Otsuka Pharmaceutical Co., Ltd.
Established August 10, 1964
President and Representative Director Makoto Inoue
Head Office 2-9, Kanda-Tsukasamachi, Chiyoda-ku, Tokyo 101-8535, Japan
Employees 5,827 (as of December 31, 2023)
Capital 20 billion yen
Business Description Manufacture, distributing, exporting and importing of pharmaceuticals, clinical testing equipment, medical device equipment, food products, cosmetics, and other related products

Major Products

Pharmaceutical Business
(Prescription drugs)
  • Antipsychotic, REXULTI / RXULTI* *brand name in EU
  • Antipsychotic, ABILIFY MAINTENA, a prolonged release aqueous suspension for intramuscular injection
  • Antipsychotic, ABILIFY
  • Dopaminergic antiparkinsonian agent, Restless legs syndrome agent, Neupro Patch
  • Therapeutic drug treatment to reduce alcohol consumption, Selincro
  • Anti-CGRP monoclonal antibody, AJOVY
  • V2-receptor antagonist , Samsca / Samtasu / JINARC* / JYNARQUE** *brand name outside Japan for ADPKD indication (**brand name in U.S.)
  • Antiplatelet agent, Pletaal
  • Anticancer agent (tyrosine kinase inhibitor), ICLUSIG
  • Conditioning agent for hematopoietic stem cell transplantation, Busulfex
  • Anti-gastritis and anti-gastric ulcer agent, Mucosta
  • Antituberculosis drug, Deltyba
  • Therapeutic agent for atopic dermatitis Moizerto
  • Therapeutic agent for dry eye, Mucosta ophthalmic suspension
  • Antiglaucoma and anti-intraocular hypertension drug, Mikeluna combination ophthalmic solution
  • COVID-19 antigen rapid diagnostic kit, Quick Navi-Covid19 Ag
  • 13C-Urea breath agent for diagnosis of H. pylori infection, UBIT
  • Test kit for the measurement of major bcr-abl mRNA, Major BCR-ABL mRNA Assay Kit “OTSUKA”
Nutraceutical Business
  • Calorie Mate
  • Fibe-Mini
  • Amino-Value
  • Kenja-no-shokutaku Double Support
  • Kenja-no-kaimin Support for healthy sleep rhythms
  • Nature Made
  • SoyCarat
  • tocoelle
  • UL・OS (Cosmedics)
  • InnerSignal (Cosmedics)
  • sakuraé(Cosmedics)

Otsuka Pharmaceutical Factory, Inc.

Otsuka Pharmaceutical Factory was first founded as Otsuka Seiyaku Kogyo-bu (Otsuka Pharmaceutical) in 1921 and is the original company from which the Otsuka group has grown. We are a leading company of IV solutions in Japan which has engaged in the IV business for over 75 years. Based on the management vision “The Best Partner in Clinical Nutrition,” we develop various innovative products to meet a wide range of needs, including Ethical Drugs, medical devices, medical foods such as oral rehydration solutions, and OTC drugs. The company also performs contract manufacturing utilizing the technologies we have developed. At present we are expanding our business operations and product development from Japan to the international market with a focus on Asia. We are determined to consistently deliver safe, high-quality products to patients and healthcare professionals.

Corporate Profile

Company Name Otsuka Pharmaceutical Factory, Inc.
Established October 7, 1969 (founded September 1, 1921)
President and Representative Director Shuichi Takagi
Head Office 115 Kuguhara, Tateiwa, Muya-cho, Naruto, Tokushima 772-8601, Japan
Employees 2,318 (As of December 31, 2023)
Capital 80 million yen
Business Description Manufacture, sale, import and export of clinical nutrition products and other pharmaceutical products, medical devices, functional foods, etc.

Major Products

Pharmaceutical Business
(Clinical Nutrition Products)
  • Amino acid, Glucose, electrolyte, multivitamin, and trace element injection for central vein infusion, ELNEOPA-NF Injection
  • Amino acid, carbohydrate, electrolyte, fat, and water-soluble vitamin injection, ENEFLUID Injection
  • Amino acid and carbohydrate injection with electrolytes and vitamin B1 for peripheral venous infusion, BFLUID Injection
  • Sodium L-Lactate Ringer’s Solution, JP, Lactec Injection
  • Multiple Electrolyte injection (1% glucose and acetated Ringer's injection), Physio 140 Injection
  • Electrolyte injection (Bicarbonated Ringer's injection), BICANATE Injection
  • Cephalosporin antibiotic for intravenous administration (Cefazolin Sodium for Injection JP), Cefazolin Sodium Injection 1g Bag Otsuka
  • Antiseptic for external use, Olanedine Solution 1.5% Antiseptic Applicator
  • Antiseptic for external use, Olanedine Solution 1.5% OR Antiseptic Applicator
  • Antiseptic for external use, Olanedine Antiseptic Solution 1.5%
  • Antiseptic for external use, Olanedine Antiseptic Solution 1.5% OR
  • Cerebrospinal irrigation and perfusion solution, ARTCEREB Irrigation and Perfusion Solution for Cerebrospinal Surgery
  • Enteral formula (for oral or tube feeding), ENORAS Liquid for Enteral Use
  • Enteral formula (for oral or tube feeding), RACOL-NF Liquid for Enteral Use
  • Enteral formula, RACOL-NF SemiSolid for Enteral Use
  • General-purpose light source, Tumguide LED Light Source
  • Gastroesophageal sterile tube and catheter for temporary use, Tumguide Fiber
  • Gel to secure the visual field used for the endoscope for natural opening, VISCOCLEAR
  • Ultrasound bladder imaging device, Lilium one
  • Ultrasound bladder imaging device, Lilium IP200
Nutraceuticals Business
(Medical Foods)
  • Oral rehydration solution, OS-1(Individually evaluated food for persons with medical conditions approved by the Consumer Affairs Agency)
  • Concentrated liquid diet, HINEX E-Gel
  • Concentrated liquid diet, HINEX E-Gel LC
  • Concentrated liquid diet, HINEX RENUTE
  • Concentrated liquid diet, HINEX Jelly
  • Comprehensive nutritional food for patients, approved by the Consumer Affairs Agency
  • HINE Jelly AQUA
  • Powdered drink, GFO
  • Beverage to support exercise and rehabilitation, REHADAYS
  • Food for persons who have difficulty swallowing, ENGELEAD (Food for special dietary use, food for persons who have difficulty swallowing, approved by the Consumer Affairs Agency: approval standard I)
  • Chew and swallow managing food, PROCESS LEAD
(OTC Drugs)
  • Product for treating minor skin conditions and injuries, Oronine H Ointment

Taiho Pharmaceutical Co.,Ltd.

Established in 1963, Taiho Pharmaceutical is an R&D-driven specialty pharma focusing on the fields of oncology and immune related diseases. Its corporate philosophy is “We strive to improve human health and contribute to a society enriched by smiles.” In the oncology field in particular, Taiho Pharmaceutical is known as one of the leading companies in Japan, actively promoting globalization as well.
In its consumer healthcare business, Taiho Pharmaceutical strives to research and develop novel and unique products by continuing to identify people’s real needs and meeting them precisely.

Corporate Profile

Company Name Taiho Pharmaceutical Co.,Ltd.
Established June 1, 1963
President and Representative Director Masayuki Kobayashi
Head Office 1-27 Kandanishiki-cho, Chiyoda-ku, Tokyo 101-8444, Japan
Employees 2,159 (As of December 31, 2023)
Capital 200 million yen
Business Description Manufacture, sales, import and export of pharmaceuticals, food supplements, sundry goods and medical devices

Major Products

Pharmaceutical Business
  • Anticancer drug, TS-1
  • Anticancer drug, Lonsurf
  • Anticancer drug, Jeselhy
  • Anticancer drug, Abraxane
  • Anticancer drug, Lytgobi
  • 5-HT3 receptor antagonist antiemetic drug, Aloxi
  • Selective NK1 receptor antagonist antiemetic drug, Arokaris
  • Antiallergic drug, Bilanoa
Nutraceuticals Business
(Consumer Healthcare products)
  • Nutritive energy drink, Tiovita series
  • Herbal digestive support drink, Solmack 5
  • Herbal medicine for mild incontinence and frequent urination, Harncare
  • Sore Throat Relief Strips, Pitas series
  • Overactive bladder medication, BUP-4 LADY

Otsuka Warehouse Co., Ltd.

Founded in 1961, Otsuka Warehouse’s core business has been centered on providing logistic services of pharmaceutical and food products. It has built a common distribution platform for the Otsuka group in the three product areas of pharmaceuticals, food and beverages, and daily necessities. In recent years, the company has grown to offer logistics services outside the group.

Corporate Profile

Company Name Otsuka Warehouse Co., Ltd.
Established November 22, 1961
President and Representative Director Kazuhiko Hamanaga
Head Office 1-3-16 Ishida, Minato-ku, Osaka 552-0006, Japan
Employees 406 (As of December 31, 2022)
Capital 800 million yen
Business Description Warehousing and transport business

Business Overview

Transportation & Warehousing

Since established in 1961, Otsuka Warehouse has been exclusively responsible for providing logistics services to group companies. In recent years, Otsuka Warehouse has expanded its business to provide logistics services to non-group companies by combining group companies' products with non-group products, according to product characteristics and seasonal variation. Utilization of such shared platform logistics system enables Otsuka Warehouse to provide non-group manufacturers with an efficient and low cost solution to their logistics needs. At the same time, Otsuka warehoue is actively engaging in a business continuity plan (BCP) to ensure that the Otsuka group fulfills its responsibility for stable product supply. Additionally, Otsuka Warehouse provides logisitics solutions by utilizing big data and cutting edge technologies.

Otsuka Chemical Co., Ltd.

Founded in 1950, Otsuka Chemical aims to improve a company that contributes for better life and better global environment in the chemical business, and deliver materials and products that meet a wide range of needs to society. It offers products and materials that meet a wide range of needs in society. As a manufacturer that develops original technologies, Otsuka Chemical supports customers and aims to continue to grow as a trusted company that provides value for society.

Corporate Profile

Company Name Otsuka Chemical Co., Ltd.
Established August 29, 1950
President and Representative Director Hiroyoshi Tosa
Head Office 3-2-27 Otedori, Chuo-ku, Osaka 540-0021, Japan
Employees 506 (As of December 31, 2022)
Capital 5 billion yen
Business Description Manufacture and sales of chemical products

Major Products

Chemical Products
  • Friction materials(friction material for brake pad), TISMO, TERRACESS
  • Compound materials, POTICON
  • Foaming agent for risin, Unifoam AZ
  • Hydrazine Derivatives
  • Pharmaceutical Intermediate, GCLE
  • High Performance Polymers, TERPLUS
  • Electrolyte solutions for EDLC, Q-CHARGE
  • Reactive Ultraviolet Absorber, RUVA-93

Otsuka Foods Co., Ltd.

Founded in 1955, Otsuka Foods manufactures, markets, and imports foods and beverages. Our corporate philosophy is “Food begins with spirit, creating deliciousness, safety, peace of mind and better health.” Based on this, we propose “new foods” that contribute to enriching people’s diets by delivering delicious taste and innovative ideas and technology and reliable quality, including Bon Curry, the world’s first commercial retort-pouch food product.

Corporate Profile

Company Name Otsuka Foods Co., Ltd.
Established May 19, 1955
President and Representative Director Goro Ikeuchi
Head Office 3-2-27, Otedori, Chuo-ku, Osaka-shi, Osaka, 540-0021, Japan
Employees 578 (as of December31, 2023)
Capital 1 billion yen
Business Description Manufacture, sale, and import and sale of food and beverages

Major Products

Consumer Products Business
  • Bon Curry
  • My Size
  • Ginza Rokusan-Tei
  • Mannanhikari
  • Zero Meat
  • Micro Magic
  • Sugoidaizu
  • RIDGE Wine

Otsuka Medical Devices Co., Ltd.

Since its establishment in February 2011, Otsuka Medical Devices Co., Ltd. has focused on developing unique solutions that improve the health and well-being of patients whose medical needs and conditions cannot yet be fulfilled by existing treatment methods. To achieve our aspiration of becoming a pioneer in the medical device industry, we combine global R&D efforts with the technology and drug discovery know-how inherent within the Otsuka group’s heritage.
We will do what it takes to offer patients new innovative treatment choices and stand true to the Otsuka corporate philosophy; “Otsuka—people creating new products for better health worldwide.”

Corporate Profile

Company Name Otsuka Medical Devices Co., Ltd.
Established February 15, 2011
President and Representative Director Noriko Tojo, President and Representative Director
Head Office 2-9, Kanda-Tsukasamachi, Chiyoda-ku, Tokyo 101-0048, Japan
Employees 136 (As of December 31, 2023)
Capital 7.55 billion yen
Business Description R&D, manufacture, and sales of medical devices and all related operations, as well as medical device operational management for companies within the Otsuka group

Major Products

Medical Device Business
  • Ultrasound Renal Denervation System*
  • Peripheral Artery Stent, BioMimics 3D Vascular Stent System
  • Stent-Type Thrombectomy Device, Tron FX Thrombectomy Device
  • Granulocyte Monocyte Adsorption Column, Adacolumn (JIMRO Co., Ltd.)
* Europe: CE mark certified US: FDA approved and available for sale Japan: Under clinical trials